The procedure for manufacturing bottles (2) containing fluids, particularly—cosmetic, medical, pharmaceutical products or the like, comprises a forming phase of a hollow body (4) having a dispensing mouth (5) that can be closed by means of removable closing means (8) comprising shutter means (10) that can be coupled with the mouth, the closing means being made in a single body with the hollow body. During the forming phase, the closing means are arranged with the shutter means substantially transversal to the direction of coupling with the dispensing mouth. After the forming phase a coupling” phase is contemplated of the shutter means with the dispensing mouth.