A denture grinding machine includes: a denture-holding table for holding dentures; a grinding tool for grinding the dentures held on the denture-holding table; a main body for holding the grinding tool; a moving mechanism for causing relative movement between the denture-holding table and the main body; and a driving mechanism for relatively driving the main body and the denture-holding table. The moving mechanism moves relatively the denture-holding table and the main body in three-dimensional coordinate directions based on grinding portion data, and the grinding tool performs grinding of the denture occlusal surface from a direction perpendicular to the occlusal surface.