Invention Grant
US08685394B2 Combination of anti-CTLA4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases 有权
抗CTLA4抗体与多种治疗方案的组合,用于增殖性疾病的协同治疗

  • Patent Title: Combination of anti-CTLA4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases
  • Patent Title (中): 抗CTLA4抗体与多种治疗方案的组合,用于增殖性疾病的协同治疗
  • Application No.: US13384900
    Application Date: 2009-10-29
  • Publication No.: US08685394B2
    Publication Date: 2014-04-01
  • Inventor: Maria Jure-Kunkel
  • Applicant: Maria Jure-Kunkel
  • Applicant Address: US NJ Princeton
  • Assignee: Bristol-Myers Squibb Company
  • Current Assignee: Bristol-Myers Squibb Company
  • Current Assignee Address: US NJ Princeton
  • Agent Stephen C. D'Amico
  • International Application: PCT/US2009/062519 WO 20091029
  • International Announcement: WO2011/011027 WO 20110127
  • Main IPC: A61K39/395
  • IPC: A61K39/395
Combination of anti-CTLA4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases
Abstract:
Compositions and methods are disclosed which are useful of the treatment and prevention of proliferative disorders. Such Compositions comprise inter alia an anti-CTLA-4 agent, e.g. ipilimumab or tremelimumab in combination with other chemotherapeutic agents such as dasatinib, imatinib, paclitaxel, gemcitabine, cisplatin or etoposide.
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