Invention Grant
- Patent Title: Chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer
- Patent Title (中): 能够抑制自身免疫,炎症和癌症过程的趋化因子结合多肽
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Application No.: US13378063Application Date: 2010-06-15
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Publication No.: US08685398B2Publication Date: 2014-04-01
- Inventor: Michal Abraham , Orly Eizenberg , Amnon Peled
- Applicant: Michal Abraham , Orly Eizenberg , Amnon Peled
- Applicant Address: IL Nes Ziona
- Assignee: Biokine Therapeutics Ltd.
- Current Assignee: Biokine Therapeutics Ltd.
- Current Assignee Address: IL Nes Ziona
- International Application: PCT/IL2010/000473 WO 20100615
- International Announcement: WO2010/146584 WO 20101223
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12N15/62 ; C07K7/08 ; C07K14/435

Abstract:
Novel polypeptides comprising a chemokine-binding peptide and an Fc fragment are disclosed. The polypeptides are capable of binding to certain chemokines so as to modulate their activity. These polypeptides can be used to modulate in vivo chemokine-dependent processes such as inflammation and autoimmunity, and to treat associated conditions.
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