Invention Grant
US08685642B2 Allele-specific copy number measurement using single nucleotide polymorphism and DNA arrays
有权
使用单核苷酸多态性和DNA阵列的等位基因特异性拷贝数测定
- Patent Title: Allele-specific copy number measurement using single nucleotide polymorphism and DNA arrays
- Patent Title (中): 使用单核苷酸多态性和DNA阵列的等位基因特异性拷贝数测定
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Application No.: US11881932Application Date: 2007-07-30
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Publication No.: US08685642B2Publication Date: 2014-04-01
- Inventor: Nicholas Michael Sampas
- Applicant: Nicholas Michael Sampas
- Applicant Address: US CA Santa Clara
- Assignee: Agilent Technologies, Inc.
- Current Assignee: Agilent Technologies, Inc.
- Current Assignee Address: US CA Santa Clara
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12N15/00 ; C12N15/11
Abstract:
Methods and systems for allelic detection and allele-specific copy number are provided herein. The described methods use identification of single nucleotide polymorphism using restriction enzymes and CGH analysis. Microarrays comprising probes designed by the described methods are provided. Also included are methods for identifying SNP sites and copy number in samples obtained from patient populations.
Public/Granted literature
- US20090035762A1 Allele-specific copy number measurement using single nucleotide polymorphism and DNA arrays Public/Granted day:2009-02-05
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