Invention Grant
- Patent Title: Method for diagnosis and prognosis of epithelial cancers
- Patent Title (中): 上皮癌诊断和预后的方法
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Application No.: US11814939Application Date: 2006-01-30
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Publication No.: US08685659B2Publication Date: 2014-04-01
- Inventor: Bruce R. Zetter , Adam S. Feldman , W. Scott McDougal
- Applicant: Bruce R. Zetter , Adam S. Feldman , W. Scott McDougal
- Applicant Address: US MA Boston US MA Boston
- Assignee: Children's Medical Center Corporation,The General Hospital Corporation
- Current Assignee: Children's Medical Center Corporation,The General Hospital Corporation
- Current Assignee Address: US MA Boston US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2006/003049 WO 20060130
- International Announcement: WO2006/081473 WO 20060803
- Main IPC: G01N33/574
- IPC: G01N33/574
Abstract:
The present invention is based on the discovery that three proteins, Cystatin B, Chaperonin 10, and Profilin are present in the urine of patients with bladder cancer, a cancer of epithelial origin. Accordingly, the present invention is directed to methods for prognostic evaluation of cancers of epithelial origin and to methods for facilitating diagnosis of cancers of epithelial origin by monitoring the presence of these markers in biological samples. The invention is also directed to markers for therapeutic efficacy.
Public/Granted literature
- US20090239245A1 METHOD FOR DIAGNOSIS AND PROGNOSIS OF EPITHELIAL CANCERS Public/Granted day:2009-09-24
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