Invention Grant
US08685669B2 Nucleic acid molecules encoding humanized antibody molecules specific for IL-31
有权
编码IL-31特异性的人源化抗体分子的核酸分子
- Patent Title: Nucleic acid molecules encoding humanized antibody molecules specific for IL-31
- Patent Title (中): 编码IL-31特异性的人源化抗体分子的核酸分子
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Application No.: US13908436Application Date: 2013-06-03
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Publication No.: US08685669B2Publication Date: 2014-04-01
- Inventor: Kent Bondensgaard , Roland Beckmann
- Applicant: ZymoGenetics, Inc. , Merck Serono S/A
- Applicant Address: US WA Seattle CH Coinsins
- Assignee: ZymoGenetics, Inc.,Merck Serono S/A
- Current Assignee: ZymoGenetics, Inc.,Merck Serono S/A
- Current Assignee Address: US WA Seattle CH Coinsins
- Agent Brian J. Walsh; Robyn Adams
- Main IPC: C12N5/10
- IPC: C12N5/10 ; C12N15/63
Abstract:
The invention provides humanized mouse anti-human IL-31 antibodies and antibody fragments that are capable of binding IL-31 and thereby neutralizing, inhibiting, limiting, or reducing the proinflammatory or pro-pruritic effects of IL-31.
Public/Granted literature
- US20130295611A1 HUMANIZED ANTIBODY MOLECULES SPECIFIC FOR IL-31 Public/Granted day:2013-11-07
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