Invention Grant
US08685689B2 Restriction endonucleases, DNA encoding these endonucleases and methods for indentifying new endonucleases with the same or varied specificity
有权
限制性内切核酸酶，编码这些内切核酸酶的DNA和用于鉴定具有相同或不同特异性的新核酸内切酶的方法
- Patent Title: Restriction endonucleases, DNA encoding these endonucleases and methods for indentifying new endonucleases with the same or varied specificity
- Patent Title (中): 限制性内切核酸酶，编码这些内切核酸酶的DNA和用于鉴定具有相同或不同特异性的新核酸内切酶的方法
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Application No.: US13490100Application Date: 2012-06-06
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Publication No.: US08685689B2Publication Date: 2014-04-01
- Inventor: Richard D. Morgan , Richard J. Roberts
- Applicant: Richard D. Morgan , Richard J. Roberts
- Applicant Address: US MA Ipswich
- Assignee: New England Biolabs, Inc.
- Current Assignee: New England Biolabs, Inc.
- Current Assignee Address: US MA Ipswich
- Agency: New England Biolabs, Inc
- Agent Harriet M. Strimpel
- Main IPC: C12N9/22
- IPC: C12N9/22
Abstract:
Specified restriction endonucleases have been characterized for the first time by their amino acid and DNA sequences. These sequences and those with at least 90% identity thereto have been used as probes in sequence similarity analyses to identify sequence matches in a sequence database that corresponds to novel restriction endonucleases or isoschizomers. The sequence similarity analyses includes selecting a positive sequence match from any sequence producing an expectation value of less than or equal to e−02.
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