Invention Grant
- Patent Title: Microorganism for the production of succinic acid
- Patent Title (中): 微生物用于生产琥珀酸
-
Application No.: US12596771Application Date: 2008-04-16
-
Publication No.: US08685704B2Publication Date: 2014-04-01
- Inventor: Christine Lang , Markus Veen , Mewes Bottner , Andreas Raab
- Applicant: Christine Lang , Markus Veen , Mewes Bottner , Andreas Raab
- Applicant Address: DE Berlin
- Assignee: Organo-Balance GmbH
- Current Assignee: Organo-Balance GmbH
- Current Assignee Address: DE Berlin
- Agency: Mayer & Williams PC
- Agent Ann Wieczorek
- Priority: DE102007019184 20070420
- International Application: PCT/DE2008/000670 WO 20080416
- International Announcement: WO2008/128522 WO 20081030
- Main IPC: C12N1/00
- IPC: C12N1/00

Abstract:
The invention relates to an isolated genetically modified microorganism in which the gene IDH1 and at least one of the genes SDH2 and DIC1 are under the control of a first promoter that is repressed to a growth culture medium by means of a cultivation additive and is active in the absence of the cultivation additive. The genes that are part of the group comprising “PYC1, ACS1, CIT1, ACO1, ICL1, MSL1, and CIT2, optionally also MDH3” are constitutively active. The invention further relates to uses of such a microorganism, especially for producing succinic acid.
Public/Granted literature
- US20110129885A1 MICROORGANISM FOR THE PRODUCTION OF SUCCINIC ACID Public/Granted day:2011-06-02
Information query