Invention Grant
- Patent Title: Antagonists of MUC1
- Patent Title (中): MUC1的拮抗剂
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Application No.: US13026858Application Date: 2011-02-14
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Publication No.: US08685928B2Publication Date: 2014-04-01
- Inventor: Donald W. Kufe , Surender Kharbanda
- Applicant: Donald W. Kufe , Surender Kharbanda
- Applicant Address: US MA Boston US IL Chicago
- Assignee: Dana-Farber Cancer Institute, Inc.,Genus Oncology, LLC.
- Current Assignee: Dana-Farber Cancer Institute, Inc.,Genus Oncology, LLC.
- Current Assignee Address: US MA Boston US IL Chicago
- Agency: Parker Highlander PLLC
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61P35/00 ; A61K9/127 ; A61K38/16
Abstract:
The present invention is directed to improved compositions for cellular delivery of peptides. Using segments of only 3-5 positively-charged residues, one can effectively transfer peptides, including therapeutic peptides, into cells. Also provided are modified peptides such as those include stapled and cyclized peptide technology, as well as peptoids/peptidomimetics.
Public/Granted literature
- US20120045502A1 ANTAGONISTS OF MUC1 Public/Granted day:2012-02-23
Information query
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