Invention Grant
- Patent Title: Sphingosine kinase inhibitor prodrugs
- Patent Title (中): 鞘氨醇激酶抑制剂前药
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Application No.: US13255813Application Date: 2010-03-12
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Publication No.: US08685936B2Publication Date: 2014-04-01
- Inventor: Charles D. Smith , Yan Zhuang , Lynn W. Maines
- Applicant: Charles D. Smith , Yan Zhuang , Lynn W. Maines
- Applicant Address: US PA Hershey
- Assignee: Apogee Biotechnology Corporation
- Current Assignee: Apogee Biotechnology Corporation
- Current Assignee Address: US PA Hershey
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- International Application: PCT/US2010/027177 WO 20100312
- International Announcement: WO2010/105183 WO 20100916
- Main IPC: A61K31/70
- IPC: A61K31/70 ; A61K31/66 ; A61K31/27 ; C07H17/00 ; C07C269/00 ; C07F9/02

Abstract:
The invention relates to prodrugs of hydroxyl-substituted adamantane compounds, pharmaceutical compositions thereof, and methods for inhibiting sphingosine kinase and for treating or preventing hyperproliferative disease, inflammatory disease, or angiogenic disease.
Public/Granted literature
- US20120058966A1 Sphingosine Kinase Inhibitor Prodrugs Public/Granted day:2012-03-08
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