Invention Grant
- Patent Title: Pyrimidine derivatives for treatment of alzheimer's disease
- Patent Title (中): 嘧啶衍生物治疗阿尔茨海默病
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Application No.: US13058231Application Date: 2009-07-31
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Publication No.: US08685972B2Publication Date: 2014-04-01
- Inventor: Alexey A. Rivkin , Sean P. Ahearn , Stephanie M. Chichetti
- Applicant: Alexey A. Rivkin , Sean P. Ahearn , Stephanie M. Chichetti
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Susan L. Hess; John C. Todaro
- International Application: PCT/US2009/052324 WO 20090731
- International Announcement: WO2010/019393 WO 20100218
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/505
Abstract:
The invention encompasses pyrimidine derivatives as gamma secretase modulators, useful for treating diseases associated with the deposition of beta-amyloid peptide in the brain, such as Alzheimer's disease, or of preventing or delaying the onset of dementia associated with such diseases. Pharmaceutical compositions and methods of use are included.
Public/Granted literature
- US20110207733A1 PYRIMIDINE DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE Public/Granted day:2011-08-25
Information query
