Invention Grant
US08686002B2 Heterocyclic compounds and their use as binding partners for 5-HT5 receptors
有权
杂环化合物及其作为5-HT 5受体的结合伴侣的用途
- Patent Title: Heterocyclic compounds and their use as binding partners for 5-HT5 receptors
- Patent Title (中): 杂环化合物及其作为5-HT 5受体的结合伴侣的用途
-
Application No.: US11990822Application Date: 2006-08-21
-
Publication No.: US08686002B2Publication Date: 2014-04-01
- Inventor: Wilhelm Amberg , Astrid Netz , Andreas Kling , Michael Ochse , Udo Lange , Charles W. Hutchins , Francisco Javier Garcia-Ladona , Wolfgang Wernet
- Applicant: Wilhelm Amberg , Astrid Netz , Andreas Kling , Michael Ochse , Udo Lange , Charles W. Hutchins , Francisco Javier Garcia-Ladona , Alfred Hahn
- Applicant Address: DE Wiesbaden
- Assignee: AbbVie Deutschland GmbH & Co. KG
- Current Assignee: AbbVie Deutschland GmbH & Co. KG
- Current Assignee Address: DE Wiesbaden
- Agency: Michael Best & Friedrich LLP
- Agent Lisa V. Mueller
- Priority: DE102005040602 20050821; DE102006005916 20060209
- International Application: PCT/EP2006/008222 WO 20060821
- International Announcement: WO2007/022946 WO 20070301
- Main IPC: C07D215/38
- IPC: C07D215/38 ; C07D239/84 ; C07D401/04 ; C07D405/06 ; C07D409/04 ; C07D409/12 ; C07D471/04 ; C07D491/04 ; A61K31/4706 ; A61P25/28

Abstract:
The invention relates to compounds of general formula (I), corresponding enantiomeric, diastereomeric and/or tautomeric forms thereof as well as pharmaceutically acceptable salts thereof and the prodrugs of said compounds. The invention also relates to the use of said compounds as binding partners for 5-HT5 receptors for treating diseases that are modulated by a 5-HT5 receptor activity, in particular, for treating neurodegenerative and neuropsychiatric disorders as well as signs, symptoms and dysfunctions.
Public/Granted literature
- US20100041698A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS Public/Granted day:2010-02-18
Information query