Invention Grant
- Patent Title: Compositions and methods for inhibiting sphingosine kinase
- Patent Title (中): 抑制鞘氨醇激酶的组合物和方法
-
Application No.: US12896881Application Date: 2010-10-02
-
Publication No.: US08686046B2Publication Date: 2014-04-01
- Inventor: Kevin R. Lynch , Timothy L. Macdonald , Yugesh Kharel , Thomas P. Mathews , Brian R. Wamhoff
- Applicant: Kevin R. Lynch , Timothy L. Macdonald , Yugesh Kharel , Thomas P. Mathews , Brian R. Wamhoff
- Applicant Address: US VA Charlottesville
- Assignee: University of Virginia Patent Foundation
- Current Assignee: University of Virginia Patent Foundation
- Current Assignee Address: US VA Charlottesville
- Agency: J. A. Lindeman & Co., PLLC
- Main IPC: A61K31/175
- IPC: A61K31/175 ; C07C257/14
Abstract:
Amidine analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumor cells.
Public/Granted literature
- US20110106241A1 COMPOSITIONS AND METHODS FOR INHIBITING SPHINGOSINE KINASE Public/Granted day:2011-05-05
Information query
IPC分类:
