Invention Grant
US08686110B2 Therapeutic pro-apoptotic BH3-like molecules and methods for generating and/or selecting the same
有权
治疗性促凋亡BH3样分子及其生成和/或选择的方法
- Patent Title: Therapeutic pro-apoptotic BH3-like molecules and methods for generating and/or selecting the same
- Patent Title (中): 治疗性促凋亡BH3样分子及其生成和/或选择的方法
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Application No.: US11993829Application Date: 2006-06-23
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Publication No.: US08686110B2Publication Date: 2014-04-01
- Inventor: Peter Malcolm Colman , David Ching Siang Huang , Erinna Faith Lee , Walter Douglas Fairlie
- Applicant: Peter Malcolm Colman , David Ching Siang Huang , Erinna Faith Lee , Walter Douglas Fairlie
- Applicant Address: AU Parkville, Victoria
- Assignee: The Walter and Eliza Hall Institute of Medical Research
- Current Assignee: The Walter and Eliza Hall Institute of Medical Research
- Current Assignee Address: AU Parkville, Victoria
- Agency: Knobbe Martens Olson & Bear, LLP
- International Application: PCT/AU2006/000888 WO 20060623
- International Announcement: WO2006/135985 WO 20061228
- Main IPC: C07K5/00
- IPC: C07K5/00 ; C12N15/00
Abstract:
The present invention relates generally to therapeutic molecules which are useful for modulating apoptosis in a target cell or cell population. More particularly, the present invention provides therapeutic agents which inhibit pro-survival molecules and which are capable of inducing or facilitating apoptosis of a target cell or cell population such as cancer cells. The present invention further provides methods for generating or selecting the therapeutic molecules and pharmaceutical compositions comprising the therapeutic molecules.
Public/Granted literature
- US20090048164A1 THERAPEUTIC PRO-APOPTOTIC BH3-LIKE MOLECULES AND METHODS FOR GENERATING AND/OR SELECTING THE SAME Public/Granted day:2009-02-19
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