Invention Grant
- Patent Title: Variants of humanized immunomodulatory monoclonal antibodies
- Patent Title (中): 人源化免疫调节单克隆抗体的变体
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Application No.: US13556018Application Date: 2012-07-23
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Publication No.: US08686119B2Publication Date: 2014-04-01
- Inventor: Rinat Rotem-Yehudar , Michael Schickler
- Applicant: Rinat Rotem-Yehudar , Michael Schickler
- Applicant Address: IL Yavne
- Assignee: CureTech Ltd.
- Current Assignee: CureTech Ltd.
- Current Assignee Address: IL Yavne
- Agency: Winston & Strawn LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395
Abstract:
The present invention relates to humanized monoclonal antibodies, pharmaceutical compositions that include the same, and use thereof for the treatment of a variety of indications, particularly cancer and immunodeficiency disorders. In particular, the present invention provides modified antibodies or fragments thereof having specific amino acid modifications compared to the humanized monoclonal immunomodulatory antibody termed hBAT-1.
Public/Granted literature
- US20130022595A1 VARIANTS OF HUMANIZED IMMUNOMODULATORY MONOCLONAL ANTIBODIES Public/Granted day:2013-01-24
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