Invention Grant
- Patent Title: Molecular conjugate
- Patent Title (中): 分子结合物
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Application No.: US12687564Application Date: 2010-01-14
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Publication No.: US08686122B2Publication Date: 2014-04-01
- Inventor: Christopher Bieniarz , Julia Ashworth-Sharpe , Casey A. Kernag , Jerome W. Kosmeder , Mark Lefever
- Applicant: Christopher Bieniarz , Julia Ashworth-Sharpe , Casey A. Kernag , Jerome W. Kosmeder , Mark Lefever
- Applicant Address: US AZ Tucson
- Assignee: Ventana Medical Systems, Inc.
- Current Assignee: Ventana Medical Systems, Inc.
- Current Assignee Address: US AZ Tucson
- Agency: Klarquist Sparkman, LLP
- Main IPC: C07K1/13
- IPC: C07K1/13 ; C07K1/10 ; G01N33/532
Abstract:
A method is disclosed for making a conjugate of two molecules using a hydrazide thiol linker. In a particular working embodiment, an Fc-specific antibody-enzyme conjugate is made using the method and demonstrated to provide exceptional staining sensitivity and specificity in immunohistochemical and in situ hybridization assays.
Public/Granted literature
- US20100136652A1 Molecular Conjugate Public/Granted day:2010-06-03
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