Invention Grant
- Patent Title: Agent for targeting c-Jun mRNA
- Patent Title (中): 用于靶向c-Jun mRNA的试剂
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Application No.: US13548142Application Date: 2012-07-12
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Publication No.: US08686128B2Publication Date: 2014-04-01
- Inventor: Levon Michael Khachigian
- Applicant: Levon Michael Khachigian
- Agency: Morrison & Foerster LLP
- Priority: AUPS0780 20020227
- Main IPC: C07H21/04
- IPC: C07H21/04
Abstract:
The present invention provides a method of preventing or reducing restenosis, neointima formation, graft failure, atherosclerosis, angiogenesis and/or solid tumor growth in a subject. The method comprises administering to the subject a prophylactically effective dose of a nucleic acid which decreases the level of c-Jun mRNA, c-Jun mRNA translation or nuclear accumulation or activity of c-Jun. It is preferred that the nucleic acid is a DNAzyme that targets c-Jun mRNA.
Public/Granted literature
- US20130237696A1 VASCULAR THERAPEUTICS Public/Granted day:2013-09-12
Information query
