Invention Grant
US08686147B2 Compound with serotoninergic activity, process for preparing it and pharmaceutical composition comprising it
有权
具有5-羟色胺能活性的化合物,其制备方法和包含其的药物组合物
- Patent Title: Compound with serotoninergic activity, process for preparing it and pharmaceutical composition comprising it
- Patent Title (中): 具有5-羟色胺能活性的化合物,其制备方法和包含其的药物组合物
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Application No.: US13003809Application Date: 2009-07-17
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Publication No.: US08686147B2Publication Date: 2014-04-01
- Inventor: Maria Alessandra Alisi , Nicola Cazzolla , Roberta Costi , Roberto Di Santo , Guido Furlotti , Angelo Guglielmotti , Lorenzo Polenzani
- Applicant: Maria Alessandra Alisi , Nicola Cazzolla , Roberta Costi , Roberto Di Santo , Guido Furlotti , Angelo Guglielmotti , Lorenzo Polenzani
- Applicant Address: IT Rome
- Assignee: Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.
- Current Assignee: Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.
- Current Assignee Address: IT Rome
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- International Application: PCT/EP2009/059216 WO 20090717
- International Announcement: WO2010/012611 WO 20100204
- Main IPC: A61K31/437
- IPC: A61K31/437 ; C07D471/06

Abstract:
Compound of formula (I) in which R1, R2 and R3 are defined in the following description, and the pharmaceutically acceptable acid-addition or base-addition salts thereof. The invention also relates to a process and an intermediate for preparing it, and to a pharmaceutical composition comprising it. The invention also relates to the use of a novel 2H-pyrrolo[3,4-c]quinoline compound for preparing a pharmaceutical composition that is active in the treatment of disturbances of the serotoninergic system.
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