Invention Grant
US08686193B2 Method for producing M-substituted phenylalkanols by means of isomerization
失效
通过异构化制备M取代的苯基链烷醇的方法
- Patent Title: Method for producing M-substituted phenylalkanols by means of isomerization
- Patent Title (中): 通过异构化制备M取代的苯基链烷醇的方法
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Application No.: US13503488Application Date: 2010-10-19
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Publication No.: US08686193B2Publication Date: 2014-04-01
- Inventor: Andreas Lanver , Klaus Ebel , Karl Beck , Ralf Pelzer , Jörg Botzem , Ulrich Griesbach
- Applicant: Andreas Lanver , Klaus Ebel , Karl Beck , Ralf Pelzer , Jörg Botzem , Ulrich Griesbach
- Applicant Address: DE Ludwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Ludwigshafen
- Agency: Novak Druce Connolly Bove + Quigg LLP
- Priority: EP09173907 20091023
- International Application: PCT/EP2010/065673 WO 20101019
- International Announcement: WO2011/048068 WO 20110428
- Main IPC: C07C45/51
- IPC: C07C45/51 ; C07C29/56 ; C07C47/22 ; A61K8/18
Abstract:
The invention relates to a process for the preparation of m-substituted phenylalkanols of the formula (I) in which R1 is C1-C5-alkyl and R2, R3, R4 and R5, independently of one another, are hydrogen or methyl, wherein a p-substituted phenylalkanol of the formula (II) in which R1, R2, R3, R4 and R5 having the meanings given under formula (I), is isomerized in the presence of a Friedel-Crafts catalyst to give an m-substituted phenylalkanol of the formula (I). From the m-substituted phenylalkanols of the formula (I) it is possible to form, by oxidation or dehydrogenation, as products of value, the corresponding aldehydes, which are known as fragrances and aroma chemicals.
Public/Granted literature
- US20120209031A1 METHOD FOR PRODUCING M-SUBSTITUTED PHENYLALKANOLS BY MEANS OF ISOMERIZATION Public/Granted day:2012-08-16
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