An amplifier circuit comprises an input, for receiving an input signal to be amplified; a preamplifier, for amplifying the input signal based on a variable gain; a power amplifier for amplifying the signal output from the preamplifier, and a variable voltage power supply for supplying one or more supply voltages to the power amplifier. The supply voltages are adjusted based on the variable gain or the input digital signal. According to other aspects of the invention, a power supply of an amplifier circuit is clocked using a clock signal, whereby the clock signal has a frequency that varies in accordance with a volume signal or an input signal.