Provided are methods and systems of managing a handoff in a multimedia communication network. Embodiments include estimating the voice quality of a communication route in the network. The voice quality may be estimated by using a total voice quality metric involving subtracting various impairments to the voice signal. Impairments may result from the type of vocoder in a communication route, the error or loss associated with RF links and network links, and delays in the communication route. After subtracting the impairments to obtain the total voice quality metric for the communication route, the total voice quality metric may be compared with a threshold and/or other total voice quality metrics of other communication routes to determine whether and when a handoff should be made.