A mouthguard has an initial, substantially linear configuration and may be worn in a variety of applications including to protect a person's teeth when the person is engaged in a sports activity such as football, lacrosse, and other contact sports, as well as for concussion protection, user performance enhancement and so forth. The mouthguard includes a first end trough region generally shaped to cooperatively enclose one or more teeth on a first side of a mouth, a second end trough region generally shaped to cooperatively enclose one or more teeth on a second side of the mouth and a connection region spanning between the first end trough region and the second trough region. The connection may include a shaping element for reversibly forming a second, generally non-linear configuration.