A ligation apparatus that ligatures living tissue using a clip and provides an optimal ligation apparatus for ligaturing living tissue in a body cavity. The ligation apparatus includes a clip with a clip claw member that is advanced and retreated relative to a pressing member to open and close, a sheath configured to accommodate the clip such that the clip claw member is not exposed to the outside, an advance and retreat restricting mechanism which restricts advance and retreat of the pressing member relative to the sheath at a distal end portion of the sheath and allows advance and retreat of the clip claw member relative to the pressing member according to advance and retreat of the operation wire relative to the sheath to allow the clip ligaturing living tissue, and a releasing mechanism which releases at least a portion of the clip when the clip ligatures the living tissue.