Invention Grant
US08691207B2 Transplantation of cells expressing markers for photoreceptor cells and retinal ganglion cells induced from Müller stem cells
有权
移植表达来自Müller干细胞诱导的感光细胞和视网膜神经节细胞标志物的细胞
- Patent Title: Transplantation of cells expressing markers for photoreceptor cells and retinal ganglion cells induced from Müller stem cells
- Patent Title (中): 移植表达来自Müller干细胞诱导的感光细胞和视网膜神经节细胞标志物的细胞
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Application No.: US13341042Application Date: 2011-12-30
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Publication No.: US08691207B2Publication Date: 2014-04-08
- Inventor: Gloria Astrid Limb , Peng Tee Khaw
- Applicant: Gloria Astrid Limb , Peng Tee Khaw
- Applicant Address: GB London
- Assignee: The Institute of Ophthalmology
- Current Assignee: The Institute of Ophthalmology
- Current Assignee Address: GB London
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: GB0328021.1 20031203
- Main IPC: A01K63/00
- IPC: A01K63/00 ; A01K65/00
Abstract:
A method for the production of retinal cells, useful in transplantation therapy, comprises: (i) obtaining one or more mammalian adult Müller cells; and (ii) culturing the cells in the presence of an extracellular matrix protein and a growth factor to thereby induce dedifferentiation of the Müller cells into a progenitor phenotype.
Public/Granted literature
- US20120100215A1 MULLER STEM CELLS Public/Granted day:2012-04-26
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