Invention Grant
US08691211B2 Suppression of immune response to factor VIII in hemophilia A patients
有权
抑制血友病A患者因子VIII的免疫反应
- Patent Title: Suppression of immune response to factor VIII in hemophilia A patients
- Patent Title (中): 抑制血友病A患者因子VIII的免疫反应
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Application No.: US12721361Application Date: 2010-03-10
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Publication No.: US08691211B2Publication Date: 2014-04-08
- Inventor: Neil Cary Josephson
- Applicant: Neil Cary Josephson
- Applicant Address: US WA Seattle
- Assignee: Puget Sound Blood Center
- Current Assignee: Puget Sound Blood Center
- Current Assignee Address: US WA Seattle
- Agency: Fenwick & West LLP
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K38/37 ; C12N5/10 ; C12N15/85
Abstract:
This invention relates to methods and compositions for suppressing an immune response to Factor VIII in subjects suffering from hemophilia A and having preformed inhibitor antibodies against Factor VIII, and compositions and methods that advantageously render subjects amenable to standard treatments for hemophilia A, including Factor VIII replacement therapy.
Public/Granted literature
- US20100233119A1 SUPPRESSION OF IMMUNE RESPONSE TO FACTOR VIII IN HEMOPHILIA A PATIENTS Public/Granted day:2010-09-16
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