Invention Grant
- Patent Title: High growth reassortant influenza A virus
- Patent Title (中): 高生长重配甲型流感病毒
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Application No.: US13140395Application Date: 2009-12-18
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Publication No.: US08691238B2Publication Date: 2014-04-08
- Inventor: Thomas Muster , Markus Wolschek , Andrej Egorov , Elisabeth Roethl , Julia Romanova , Michael Bergmann
- Applicant: Thomas Muster , Markus Wolschek , Andrej Egorov , Elisabeth Roethl , Julia Romanova , Michael Bergmann
- Applicant Address: CH Opfikon
- Assignee: Baxter Healthcare SA
- Current Assignee: Baxter Healthcare SA
- Current Assignee Address: CH Opfikon
- Agency: Loza & Loza, LLP
- Agent Michael Fedrick
- Priority: EP09155992 20090324
- International Application: PCT/EP2009/067523 WO 20091218
- International Announcement: WO2010/070098 WO 20100624
- Main IPC: A61K39/145
- IPC: A61K39/145 ; A61K39/12 ; C12N7/08

Abstract:
The present invention provides a high growth reassortant influenza A virus having at least two gene segments of seasonal or pandemic strain origin, a PB1 gene segment of A/Texas/1/77 strain origin and a PA gene segment of A/Puerto Rico/8/34 (H1N1) origin coding for a PA protein comprising at least one amino acid modification at any one of positions 10, 275, 682, according to SEQ ID No. 1. Further provided are vaccine formulations comprising the reassortant influenza A virus of the invention.
Public/Granted literature
- US20110262481A1 HIGH GROWTH REASSORTANT INFLUENZA A VIRUS Public/Granted day:2011-10-27
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