Invention Grant
US08691511B2 Hydroxylated 1,2,4-oxadiazole benzoic acid compounds, compositions thereof and their use in bioassays
有权
羟基化的1,2,4-恶二唑苯甲酸化合物，其组合物及其在生物测定中的用途
- Patent Title: Hydroxylated 1,2,4-oxadiazole benzoic acid compounds, compositions thereof and their use in bioassays
- Patent Title (中): 羟基化的1,2,4-恶二唑苯甲酸化合物，其组合物及其在生物测定中的用途
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Application No.: US13327816Application Date: 2011-12-16
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Publication No.: US08691511B2Publication Date: 2014-04-08
- Inventor: Neil G. Almstead , Peter Seongwoo Hwang , Young-Choon Moon , Ellen M. Welch
- Applicant: Neil G. Almstead , Peter Seongwoo Hwang , Young-Choon Moon , Ellen M. Welch
- Applicant Address: US NJ South Plainfield
- Assignee: PTC Therapeutics, Inc.
- Current Assignee: PTC Therapeutics, Inc.
- Current Assignee Address: US NJ South Plainfield
- Agency: Jones Day
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07D271/06 ; A61K31/41 ; C12P21/04
Abstract:
Novel hydroxylated 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising a hydroxylated 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.
Public/Granted literature
- US20120087896A1 HYDROXYLATED 1,2,4-OXADIAZOLE BENZOIC ACID COMPOUNDS, COMPOSITIONS THEREOF AND THEIR USE IN BIOASSAYS Public/Granted day:2012-04-12
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