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US08691516B2 Mutant microorganism producing succinic acid simultaneously using sucrose and glycerol, and method for preparing succinic acid using same 有权
使用蔗糖和甘油同时生产琥珀酸的突变体微生物，以及使用其制备琥珀酸的方法

Mutant microorganism producing succinic acid simultaneously using sucrose and glycerol, and method for preparing succinic acid using same
Abstract:
The present invention relates to a succinic acid-producing mutant microorganism that is able to utilize sucrose and glycerol simultaneously as carbon sources. More particularly, the present invention relates to a succinic acid-producing mutant microorganism that is able to utilize sucrose and glycerol simultaneously for succinic acid production, the mutant organism being obtained by relieving the mechanism of sucrose-mediated catabolite repression of glycerol in a succinic acid-producing microorganism. As described above, when the succinic acid-producing mutant microorganism is cultured, it utilizes sucrose and glycerol simultaneously so that succinic acid can be produced with high productivity in a maximum yield approaching the theoretical yield while the production of byproducts is minimized. In addition, according to the present invention, various reduced chemicals which have been produced in low yields in conventional methods can be more effectively produced.
Abstract(Chinese):

本发明涉及能够同时使用蔗糖和甘油作为碳源的产琥珀酸突变体微生物。 更具体地，本发明涉及能够同时使用蔗糖和甘油进行琥珀酸生产的产琥珀酸的突变体微生物，其通过减轻甘油在琥珀酸中的蔗糖介导的分解代谢物抑制的机制而获得 生产微生物。 如上所述，当培养产琥珀酸的突变体微生物时，它同时使用蔗糖和甘油，使得以最大产率接近理论产率的高生产率生产琥珀酸，同时副产物的产生最小化。 此外，根据本发明，可以更有效地制造在常规方法中以低收率生产的各种还原化学品。

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