Invention Grant
- Patent Title: Inducible gene expression
- Patent Title (中): 诱导型基因表达
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Application No.: US11658206Application Date: 2005-08-03
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Publication No.: US08691533B2Publication Date: 2014-04-08
- Inventor: Frank Notka , Ralf Wagner , Diana Hammer
- Applicant: Frank Notka , Ralf Wagner , Diana Hammer
- Applicant Address: DE Regensburg
- Assignee: GeneArt AG
- Current Assignee: GeneArt AG
- Current Assignee Address: DE Regensburg
- Priority: DE102004037611 20040803
- International Application: PCT/EP2005/008427 WO 20050803
- International Announcement: WO2006/013103 WO 20060209
- Main IPC: C12N5/10
- IPC: C12N5/10 ; C12N7/01 ; C12N15/00 ; C12N15/33 ; A61K48/00
Abstract:
The invention relates to vector constructs for an HIV-specific gene therapy. The expression of transgenes is coupled with an infection of the cell with HIV while the transcription of the transgene is controlled by a transcription control region derived from HIV. In addition, the transgene is improved with regard to RNA stability and expression efficiency by modifying the nucleotide sequence.
Public/Granted literature
- US20110033429A1 Inducible Gene Expression Public/Granted day:2011-02-10
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