Invention Grant
US08691585B2 Methods for predicting pregnancy outcome in a subject by hCG assay
有权
通过hCG检测预测受试者妊娠结局的方法
- Patent Title: Methods for predicting pregnancy outcome in a subject by hCG assay
- Patent Title (中): 通过hCG检测预测受试者妊娠结局的方法
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Application No.: US13150791Application Date: 2011-06-01
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Publication No.: US08691585B2Publication Date: 2014-04-08
- Inventor: John F. O'Connor , Galina I. Kovalevskaya , Steven Birken
- Applicant: John F. O'Connor , Galina I. Kovalevskaya , Steven Birken
- Applicant Address: US NY New York
- Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee Address: US NY New York
- Agency: Cooper & Dunham LLP
- Agent John P. White
- Main IPC: G01N33/48
- IPC: G01N33/48 ; G01N33/00 ; A61K49/00
Abstract:
The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
Public/Granted literature
- US20110256554A1 METHODS FOR PREDICTING PREGNANCY OUTCOME IN A SUBJECT BY HCG ASSAY Public/Granted day:2011-10-20
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