Invention Grant
- Patent Title: Use of SFRP-3 in the assessment of heart failure
- Patent Title (中): 使用SFRP-3评估心力衰竭
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Application No.: US12901691Application Date: 2010-10-11
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Publication No.: US08691587B2Publication Date: 2014-04-08
- Inventor: Ursula-Henrike Wienhues-Thelen , Sara Arab , Dirk Block , Andrew Emili , Anthony Gramolini , Georg Hess , Hendrik Heudig , Peter Liu , David MacLennan
- Applicant: Ursula-Henrike Wienhues-Thelen , Sara Arab , Dirk Block , Andrew Emili , Anthony Gramolini , Georg Hess , Hendrik Heudig , Peter Liu , David MacLennan
- Applicant Address: US IN Indianapolis
- Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee Address: US IN Indianapolis
- Agency: Roche Diagnostics Operations, Inc.
- Priority: EP08008304 20080430
- Main IPC: G01N33/00
- IPC: G01N33/00 ; G01N33/537
Abstract:
Disclosed is a method for assessing heart failure in vitro including the steps of measuring in a sample the concentration of the marker SFRP-3, of optionally measuring in the sample the concentration of one or more other marker(s) of heart failure, and of assessing heart failure by comparing the concentration determined in for SFRP-3 and the concentration(s) determined for the optionally one or more other marker to the concentration of this marker or these markers as established in a reference population. Also disclosed are the use of SFRP-3 as a marker protein in the assessment of heart failure, a marker combination comprising SFRP-3 and a kit for measuring SFRP-3.
Public/Granted literature
- US20110027819A1 USE OF SFRP-3 IN THE ASSESSMENT OF HEART FAILURE Public/Granted day:2011-02-03
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