Invention Grant
US08691766B2 Biglycan and related therapeutics and methods of use 有权
Biglycan及相关疗法及使用方法

Biglycan and related therapeutics and methods of use
Abstract:
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Example of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders.
Public/Granted literature
Information query
Patent Agency Ranking
0/0