Invention Grant
US08691780B2 Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby
失效
Txr1和增强的紫杉烷敏感性基于由其介导的途径的调节
- Patent Title: Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby
- Patent Title (中): Txr1和增强的紫杉烷敏感性基于由其介导的途径的调节
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Application No.: US11357728Application Date: 2006-02-16
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Publication No.: US08691780B2Publication Date: 2014-04-08
- Inventor: Chih Jian Lih , Stanley N. Cohen
- Applicant: Chih Jian Lih , Stanley N. Cohen
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: Bozicevic, Field & Francis LLP
- Agent Bret E. Field; Kyle A. Gurley
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K31/337 ; A61K31/341

Abstract:
Methods and compositions for enhancing taxane sensitivity are provided. Aspects of the subject methods include administering to a subject a txr1 pathway modulatory agent in conjunction with a taxane. Also provided are txr1 polypeptides and nucleic acids encoding the same. The subject methods and compositions find use in a variety of different applications.
Public/Granted literature
- US20070209082A1 Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby Public/Granted day:2007-09-06
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