Invention Grant
US08691790B2 Therapy of neurological inflammatory diseases with (5'-deoxy-5'-adenosyl) cobamamide, recombinant human growth hormone, interleukins IL-1, IL-6, IL-11, epidermal growth factor, and physiotherapy
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（5'-脱氧-5'-腺苷）cobamamide，重组人生长激素，白介素IL-1，IL-6，IL-11，表皮生长因子和物理疗法治疗神经炎症性疾病
- Patent Title: Therapy of neurological inflammatory diseases with (5'-deoxy-5'-adenosyl) cobamamide, recombinant human growth hormone, interleukins IL-1, IL-6, IL-11, epidermal growth factor, and physiotherapy
- Patent Title (中): （5'-脱氧-5'-腺苷）cobamamide，重组人生长激素，白介素IL-1，IL-6，IL-11，表皮生长因子和物理疗法治疗神经炎症性疾病
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Application No.: US12460946Application Date: 2009-07-27
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Publication No.: US08691790B2Publication Date: 2014-04-08
- Inventor: James Layne Boucher
- Applicant: James Layne Boucher
- Main IPC: A01N43/04
- IPC: A01N43/04
Abstract:
A novel etiological hypothesis for Multiple Sclerosis (MS) is proposed describing autoimmune attack of ATP: Cob(I)alamin adenosyltransferase (ATR) thereby inhibiting synthesis of (5′-deoxy-5′-adenosyl)cobamide (referred to as 5′-deoxyadenosylcobalmin or AdoCbl) from Vitamin B 12 providing a basis for therapeutic design and diagnostic methods. Pharmaceutical compositions for therapy of MS, inflammatory neurological diseases and neurodegenerative diseases utilizing AdoCbl, growth hormones, immunomodulators, interleukins, other therapeutic agents, and physiotherapy are also described.
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