Invention Grant
US08691823B2 Prodrugs of (4aS, 13ar)-N-[(2,4-difluorophenyl)methyl]-10-hydroxy-9-11-dioxo-2,3,4a,5,9,11,13,13a-octahydro-1H-pyrido[1,2-a]pyrrolo[1′,2′:3:4]imidazo[1,2-d]pyrazine-8-carboxamide and their use in the treatment of HIV infection
有权
（4aS，13ar）-N - [（2,4-二氟苯基）甲基] -10-羟基-9-11-二氧代-2,3,4a，5,9,11,13,13a-八氢-1H- - 吡咯并[1,2-a]吡咯并[1'，2'：3：4]咪唑并[1,2-d]吡嗪-8-甲酰胺及其在治疗HIV感染中的用途
![Prodrugs of (4aS, 13ar)-N-[(2,4-difluorophenyl)methyl]-10-hydroxy-9-11-dioxo-2,3,4a,5,9,11,13,13a-octahydro-1H-pyrido[1,2-a]pyrrolo[1′,2′:3:4]imidazo[1,2-d]pyrazine-8-carboxamide and their use in the treatment of HIV infection](/docs/US/2014-04-08/US08691823B2/abs.jpg.600x600.jpg)
- Patent Title: Prodrugs of (4aS, 13ar)-N-[(2,4-difluorophenyl)methyl]-10-hydroxy-9-11-dioxo-2,3,4a,5,9,11,13,13a-octahydro-1H-pyrido[1,2-a]pyrrolo[1′,2′:3:4]imidazo[1,2-d]pyrazine-8-carboxamide and their use in the treatment of HIV infection
- Patent Title (中): （4aS，13ar）-N - [（2,4-二氟苯基）甲基] -10-羟基-9-11-二氧代-2,3,4a，5,9,11,13,13a-八氢-1H- - 吡咯并[1,2-a]吡咯并[1'，2'：3：4]咪唑并[1,2-d]吡嗪-8-甲酰胺及其在治疗HIV感染中的用途
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Application No.: US13770336Application Date: 2013-02-19
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Publication No.: US08691823B2Publication Date: 2014-04-08
- Inventor: Brian A. Johns , Jason G. Weatherhead , Yasunori Aoyama , Hiroshi Yoshida , Yoshiyuki Taoda
- Applicant: Shionogi & Co., Ltd. , GlaxoSmithKline LLC
- Applicant Address: JP Osaka US NC Research Triangle Park
- Assignee: Shionogi & Co., Ltd.,ViiV Healthcare Company
- Current Assignee: Shionogi & Co., Ltd.,ViiV Healthcare Company
- Current Assignee Address: JP Osaka US NC Research Triangle Park
- Agency: Wenderoth, Lind & Ponack, LLP.
- Main IPC: A61K31/495
- IPC: A61K31/495
![Prodrugs of (4aS, 13ar)-N-[(2,4-difluorophenyl)methyl]-10-hydroxy-9-11-dioxo-2,3,4a,5,9,11,13,13a-octahydro-1H-pyrido[1,2-a]pyrrolo[1′,2′:3:4]imidazo[1,2-d]pyrazine-8-carboxamide and their use in the treatment of HIV infection](/abs-image/US/2014/04/08/US08691823B2/abs.jpg.150x150.jpg)
Abstract:
The present invention features compounds of formula (I) for the treatment or prevention of HIV infection and for the treatment of AIDS and ARC.
Public/Granted literature
- US20130165415A1 CHEMICAL COMPOUNDS Public/Granted day:2013-06-27
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