Invention Grant
- Patent Title: D2 antagonists, methods of synthesis and methods of use
- Patent Title (中): D2拮抗剂,合成方法和使用方法
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Application No.: US13163592Application Date: 2011-06-17
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Publication No.: US08691836B2Publication Date: 2014-04-08
- Inventor: Gary W. Luehr , Arathi Sundaram , Priyadarshini Jaishankar , Philip W. Payne , Pascal Druzgala
- Applicant: Gary W. Luehr , Arathi Sundaram , Priyadarshini Jaishankar , Philip W. Payne , Pascal Druzgala
- Applicant Address: US CA Los Altos
- Assignee: Altos Therapeutics, LLC
- Current Assignee: Altos Therapeutics, LLC
- Current Assignee Address: US CA Los Altos
- Agency: Foley & Lardner LLP
- Main IPC: A61K31/438
- IPC: A61K31/438 ; C07D471/10

Abstract:
Provided are D2 or D3 antagonist compounds and pharmaceutical compositions of formula I and pharmaceutically acceptable salts thereof, or isomers thereof, wherein R1, R2 and R3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D2 or D3 receptor from the compounds of the invention.
Public/Granted literature
- US20120010228A1 D2 ANTAGONISTS, METHODS OF SYNTHESIS AND METHODS OF USE Public/Granted day:2012-01-12
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