Invention Grant
- Patent Title: Piperidine sulphonamide derivatives
- Patent Title (中): 哌啶磺酰胺衍生物
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Application No.: US13855470Application Date: 2013-04-02
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Publication No.: US08691846B2Publication Date: 2014-04-08
- Inventor: Henner Knust , Matthias Nettekoven , Emmanuel Pinard , Olivier Roche , Mark Rogers-Evans
- Applicant: Hoffmann-La Roche, Inc.
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Priority: EP08151328 20080212
- Main IPC: A61K31/4545
- IPC: A61K31/4545 ; C07D401/14

Abstract:
The present invention relates to piperidine sulphonamide derivatives of formula wherein Ar1, Ar2, R1, R2, m and n are as defined in the description and claims, or pharmaceutically suitable acid addition salts thereof. The compounds of formula I are orexin receptor antagonists and the related compounds can be useful in the treatment of sleep apnea, narcolepsy, insomnia, parasomnia, jet lag syndrome, circadian rhythms disorder or sleep disorders associated with neurological diseases.
Public/Granted literature
- US20130217729A1 PIPERIDINE SULPHONAMIDE DERIVATIVES Public/Granted day:2013-08-22
Information query
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