Invention Grant
- Patent Title: Neprilysin inhibitors
- Patent Title (中): Neprilysin抑制剂
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Application No.: US13666538Application Date: 2012-11-01
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Publication No.: US08691868B2Publication Date: 2014-04-08
- Inventor: Adam D. Hughes , Erik Fenster , Melissa Fleury , Roland Gendron , Edmund J. Moran
- Applicant: Adam D. Hughes , Erik Fenster , Melissa Fleury , Roland Gendron , Edmund J. Moran
- Applicant Address: US CA South San Francisco
- Assignee: Theravance, Inc.
- Current Assignee: Theravance, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Jeffrey A. Hagenah; Shelley Eberle
- Main IPC: A01N37/00
- IPC: A01N37/00 ; A61K31/21
Abstract:
In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
Public/Granted literature
- US20130109639A1 NEPRILYSIN INHIBITORS Public/Granted day:2013-05-02
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