Invention Grant
- Patent Title: Pharmaceutical formulation of nitrooxyderivatives of NSAIDs
- Patent Title (中): NSAIDs硝基氧化酶药物制剂
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Application No.: US11997094Application Date: 2006-06-29
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Publication No.: US08691869B2Publication Date: 2014-04-08
- Inventor: Ulla Gasslander , Christina Holmberg
- Applicant: Ulla Gasslander , Christina Holmberg
- Applicant Address: FR Sophia Antipolis
- Assignee: Nicox S.A.
- Current Assignee: Nicox S.A.
- Current Assignee Address: FR Sophia Antipolis
- Agency: Arent Fox LLP
- Priority: EP05106854 20050726
- International Application: PCT/EP2006/063672 WO 20060629
- International Announcement: WO2007/012539 WO 20070201
- Main IPC: A01N37/00
- IPC: A01N37/00 ; A61K31/21 ; C07C229/00 ; C07C239/00 ; C07C259/00
Abstract:
The present invention relates to a pharmaceutical formulation comprising: a) one or more NO-releasing NSAID(s) of formula (I); b) one or more surfactants; c) a carbonyl scavenger compound selected from free acid forms, salts, carboxylic acid esters derivatives of a compound of formula (II) H2N—(CH2)m—(C6H4)—COOH (II) wherein m=0-10; and d) optionally an oil or semi-solid fat and/or a short-chain alcohol.
Public/Granted literature
- US20090203759A1 PHARMACEUTICAL FORMULATION OF NITROOXYDERIVATIVES OF NSAIDS Public/Granted day:2009-08-13
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