Invention Grant
- Patent Title: Method for expanding monocytes
- Patent Title (中): 扩增单核细胞的方法
-
Application No.: US12522302Application Date: 2008-01-10
-
Publication No.: US08691964B2Publication Date: 2014-04-08
- Inventor: Michael Sieweke
- Applicant: Michael Sieweke
- Applicant Address: FR Paris Cedex
- Assignee: INSERM (Institut Naitonal de la Sante et de la Recherche Medicale)
- Current Assignee: INSERM (Institut Naitonal de la Sante et de la Recherche Medicale)
- Current Assignee Address: FR Paris Cedex
- Agency: McAndrews, Held & Malloy Ltd.
- Priority: EP07300717 20070111
- International Application: PCT/EP2008/050221 WO 20080110
- International Announcement: WO2008/084069 WO 20080717
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/00
Abstract:
The invention relates to an ex vivo method for expanding monocytes, macrophages or dendritic cells, which method comprises inhibiting the expression or the activity of MafB and c-Maf in monocytes, macrophages or dendritic cells; and expanding the cells in the presence of at least one cytokine or an agonist of cytokine receptor signaling.
Public/Granted literature
- US20100003272A1 Method for Expanding Monocytes Public/Granted day:2010-01-07
Information query
