Invention Grant
- Patent Title: Octahydro biquinoline compound
- Patent Title (中): 八氢异喹啉化合物
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Application No.: US13262604Application Date: 2010-05-17
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Publication No.: US08691992B2Publication Date: 2014-04-08
- Inventor: Teck Peng Loh , Jian Xiao
- Applicant: Teck Peng Loh , Jian Xiao
- Applicant Address: SG Singapore
- Assignee: Nanyang Technological University
- Current Assignee: Nanyang Technological University
- Current Assignee Address: SG Singapore
- Agency: Seed IP Law Group PLLC
- International Application: PCT/SG2010/000188 WO 20100517
- International Announcement: WO2010/132029 WO 20101118
- Main IPC: C07D215/38
- IPC: C07D215/38

Abstract:
The present invention relates to an octahydro biquinoline compound. Provided is also a method of separating the octahydro biquinoline compound into enantiomers. The octahydro biquinoline compound is of the general formula (V): In formula (V) R1 is one of H, a protective group and an aliphatic group, with the aliphatic group having a main chain of a length of 1 to about 10 carbon atoms, comprising 0 to about 6 heteroatoms selected from the group consisting of N, O, S, Se and Si. R2 and R3 are independent from one another selected from the group consisting of (i) H, (ii) one of an aliphatic, an alicyclic, an aromatic, an arylaliphatic, and an arylalicyclic group comprising 0 to about 6 heteroatoms selected from the group consisting of N, O, S, Se and Si, an ester, a carbonate group, a carbamoyl group and a phosphate ester. R4 and R5 are independent from one another H, an aliphatic, an alicyclic, an aromatic, an arylaliphatic or an arylalicyclic group comprising 0 to about 6 heteroatoms selected from the group consisting of N, O, S, Se and Si.
Public/Granted literature
- US20120088916A1 OCTAHYDRO BIQUINOLINE COMPOUND Public/Granted day:2012-04-12
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