Invention Grant
- Patent Title: Piperidinyl naphthylacetic acids
- Patent Title (中): 哌啶基萘基乙酸
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Application No.: US13706497Application Date: 2012-12-06
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Publication No.: US08691993B2Publication Date: 2014-04-08
- Inventor: Fariborz Firooznia , Tai-An Lin , Eric Mertz , Achyutharao Sidduri , Sung-Sau So , Jefferson Wright Tilley
- Applicant: Hoffman-La Roche Inc.
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Main IPC: C07D211/00
- IPC: C07D211/00 ; C07D295/00 ; C07D211/06 ; A61K31/445

Abstract:
The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and X are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
Public/Granted literature
- US20130150407A1 PIPERIDINYL NAPHTHYLACETIC ACIDS Public/Granted day:2013-06-13
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