Invention Grant
- Patent Title: Method of preparing Neramexane or a salt thereof
- Patent Title (中): 制备Neramexane或其盐的方法
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Application No.: US13498432Application Date: 2010-09-24
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Publication No.: US08692021B2Publication Date: 2014-04-08
- Inventor: Markus-Rene Gold , Valerjans Kauss , Aigars Jirgensons
- Applicant: Markus-Rene Gold , Valerjans Kauss , Aigars Jirgensons
- Applicant Address: DE Frankfurt am Main
- Assignee: Merz Pharma GmbH & Co. KGaA
- Current Assignee: Merz Pharma GmbH & Co. KGaA
- Current Assignee Address: DE Frankfurt am Main
- Agency: Hueschen and Sage
- Priority: EP09012283 20090928
- International Application: PCT/EP2010/005864 WO 20100924
- International Announcement: WO2011/035924 WO 20110331
- Main IPC: C07C211/00
- IPC: C07C211/00
Abstract:
Method of preparing 1-amino-1,3,3,5,5-pentamethylcyclohexane or a pharmaceutically acceptable salt thereof (Neramexane), comprising step (iv): (iv) hydrolyzing a mixture comprising an acid, 1-formamido-1,3,3,5,5-pentamethylcyclohexane and hydrogen cyanide to yield 1-amino-1,3,3,5,5-pentamethylcyclohexane.
Public/Granted literature
- US20120245391A1 METHOD OF PREPARING NERAMEXANE OR A SALT THEREOF Public/Granted day:2012-09-27
Information query
