Certain examples provide systems and methods for mobile virtual colonoscopy. Certain examples provide a mobile device configured to view clinical content. The mobile device includes a data storage to store data including images for a virtual colonoscopy; a user interface to display the images for user viewing and manipulation; and a motion detector to capture movement of the mobile device with respect to a reference plane and to provide movement data. The mobile device includes a processor to receive input via the user interface and provide content, including the images, to the user interface. The processor is to provide a virtual colonoscopy using the images to a user via the user interface. The processor receives the movement data from the motion detector and translates the movement data to navigation commands in the virtual colonoscopy to allow the user to conduct a virtual colonoscopy using the mobile device.