Embodiments of the invention are generally directed to video frame synchronization. An embodiment of a method includes receiving a first video data stream from a first source at a first port of a multi-port device, a first video frame of the first video data stream arriving at the first port at a first arrival time, and receiving a second video data stream from a second source at a second port of the multi-port device, a second video frame of the second video data stream arriving at the second port at a second arrival time. The method further includes determining an offset between the first arrival time and the second arrival time, determining one or more correction factors based at least in part on the offset, the one or more correction factors including a first correction factor for the first source, and sending a first command to the first source to modify a time of transmission by the first source of a third video frame following the first frame using the correction factor.