A PCIe bus extension system, method, interface card and cable for connecting a PCIe-compliant peripheral device to a PCIe bus of a computer system. The interface card includes a printed circuit board, an edge connector adapted for insertion into a PCIe expansion slot on a motherboard of the computer system for transmitting PCIe signals between the motherboard and the interface card, an interface port configured to mate with a connector of the cable, and a logic integrated circuit on the printed circuit board, the logic integrated circuit functionally connecting the edge connector with the expansion slot and amplifying and propagating clock and data PCIe signals therebetween that are compliant with a PCIe standard. The interface card and cable lacks the capability of transmitting power therethrough to a PCIe-compliant peripheral device connected to the interface card through the interface port.