Certain aspects of a method and system for optimum channel equalization between a host Serializer-Deserializer (SerDes) and an optical module may compensate and reduce dispersion loss along an electrical transmit path of a transmitter and an optical transmit path coupled to the transmitter via pre-emphasis. The data degradation as a result of the dispersion loss along the electrical transmit path of the transmitter and the optical transmit path coupled to the transmitter may be recovered by equalizing signals received via an electrical receive path of a receiver communicatively coupled to the transmitter.