Invention Grant
- Patent Title: Method for determining the binding of a given compound to a membrane receptor
- Patent Title (中): 确定给定化合物与膜受体结合的方法
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Application No.: US13388150Application Date: 2010-08-12
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Publication No.: US08697372B2Publication Date: 2014-04-15
- Inventor: Eric Trinquet , Jurriaan Zwier , Gérard Mathis , Jean-Philippe Pin , Thierry Durroux
- Applicant: Eric Trinquet , Jurriaan Zwier , Gérard Mathis , Jean-Philippe Pin , Thierry Durroux
- Applicant Address: FR Gif sure Yvette Cedex FR Paris
- Assignee: CIS Bio International,Centre National de la Recherche Scientifique
- Current Assignee: CIS Bio International,Centre National de la Recherche Scientifique
- Current Assignee Address: FR Gif sure Yvette Cedex FR Paris
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: FR0955667 20090813
- International Application: PCT/FR2010/051700 WO 20100812
- International Announcement: WO2011/018586 WO 20110217
- Main IPC: G01N33/566
- IPC: G01N33/566 ; C07K19/00 ; C07K14/705
Abstract:
The invention relates to a method for determining whether a test compound binds preferentially to a membrane receptor R1 or to a membrane receptor R2, these receptors being known to be expressed on the surface of the cells in monomeric, homodimeric or heterodimeric form. This method is applied using one or two FRET partner pairs.
Public/Granted literature
- US20120190048A1 METHOD FOR DETERMINING THE BINDING OF A GIVEN COMPOUND TO A MEMBRANE RECEPTOR Public/Granted day:2012-07-26
Information query
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