Invention Grant
- Patent Title: TMEM22 peptides and vaccines including the same
- Patent Title (中): TMEM22肽和疫苗包括它们
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Application No.: US13515656Application Date: 2010-12-13
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Publication No.: US08697631B2Publication Date: 2014-04-15
- Inventor: Yusuke Nakamura , Takuya Tsunoda , Ryuji Ohsawa , Sachiko Yoshimura , Tomohisa Watanabe
- Applicant: Yusuke Nakamura , Takuya Tsunoda , Ryuji Ohsawa , Sachiko Yoshimura , Tomohisa Watanabe
- Applicant Address: JP Kanagawa
- Assignee: OncoTherapy Science, Inc.
- Current Assignee: OncoTherapy Science, Inc.
- Current Assignee Address: JP Kanagawa
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/JP2010/007228 WO 20101213
- International Announcement: WO2011/074236 WO 20110623
- Main IPC: C07K7/06
- IPC: C07K7/06 ; A61K38/08 ; G01N33/53

Abstract:
Isolated peptides composed of the amino acid sequence of SEQ ID NO: 33 or fragments thereof that bind to HLA antigens and have cytotoxic T lymphocyte (CTL) inducibility and thus are suitable for use in the context of cancer immunotherapy, more particularly cancer vaccines are described herein. The present invention further provides peptides that include one, two, or several amino acid insertions, substitutions or additions to the aforementioned peptides or fragments, but yet retain the requisite cytotoxic T cell inducibility. Further provided are nucleic acids encoding any of these aforementioned peptides as well as pharmaceutical agents, substances and compositions including any of the aforementioned peptides or nucleic acids. The peptides, nucleic acids, pharmaceutical agents, substances and compositions of this invention find particular utility in the treatment of cancers and tumors.
Public/Granted literature
- US20120308591A1 TMEM22 PEPTIDES AND VACCINES INCLUDING THE SAME Public/Granted day:2012-12-06
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